Synthesis And Preliminary Dna-Interaction Studies Of A New Cationic Porphyrin

Document Type

Article

Publication Date

1990

Published In

Tetrahedron Letters

Abstract

A new water-soluble porphyrin containing benzyl-trimethylammonium groups was synthesized in a two-step sequence from tetraphenylporphyrin and preliminary studies show that it binds strongly to DNA in an outside manner and gives fairly stable complexes with nucleotides and nucleosides. A new water-soluble porphyrin containing benzyl-trimethylammonium groups was synthesized in a two-step sequence and preliminary studies show that it binds strongly to DNA in an outside manner.

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