Interactions Of Water-Soluble Zinc Porphyrin With Amino Acids
Document Type
Article
Publication Date
12-1-1988
Published In
Inorganica Chimica Acta: Bioinorganic Chemistry
Abstract
Equilibrium constants for replacement in aqueous solution of the axial ligand of tetrakis(4-N-methyl-pyridyl)porphinezinc(II) by a variety of amino acids at pH 9 have been determined spectrophotometrically. In addition, the equilibrium constant was determined for glycine as a function of pH. From the pH studies, it appears that the substitution of glycine of OH− at the Zn center is thermodynamically less favorable than for replacement of H₂O. Stabilization due to intramolecular non-covalent bonding between side-chains of several L-amino acids and the porphyrin macrocycle has also been observed.
Recommended Citation
E. Mikros, A. Gaudemer, and Robert F. Pasternack.
(1988).
"Interactions Of Water-Soluble Zinc Porphyrin With Amino Acids".
Inorganica Chimica Acta: Bioinorganic Chemistry.
Volume 153,
Issue 4.
199-200.
DOI: 10.1016/S0020-1693(00)88867-2
https://works.swarthmore.edu/fac-chemistry/132