Mitotic Membrane Turnover Coordinates Differential Induction Of The Heart Progenitor Lineage
In the ascidian Ciona intestinalis, nascent heart progenitor cells inherit an adherent membrane associated with elevated levels of FGFR signaling. Cota and Davidson now explain the basis for this observation, showing that adhesion, via effects on Caveolin-rich membrane domains, limits FGFR internalization, leading to receptor enrichment at the adherent membrane.
C. D. Cota and Bradley Justin Davidson , '91.
"Mitotic Membrane Turnover Coordinates Differential Induction Of The Heart Progenitor Lineage".