Mitotic Membrane Turnover Coordinates Differential Induction Of The Heart Progenitor Lineage
Document Type
Article
Publication Date
9-14-2015
Published In
Developmental Cell
Abstract
In the ascidian Ciona intestinalis, nascent heart progenitor cells inherit an adherent membrane associated with elevated levels of FGFR signaling. Cota and Davidson now explain the basis for this observation, showing that adhesion, via effects on Caveolin-rich membrane domains, limits FGFR internalization, leading to receptor enrichment at the adherent membrane.
Recommended Citation
C. D. Cota and Bradley Justin Davidson , '91.
(2015).
"Mitotic Membrane Turnover Coordinates Differential Induction Of The Heart Progenitor Lineage".
Developmental Cell.
Volume 34,
Issue 5.
505-519.
DOI: 10.1016/j.devcel.2015.07.001
https://works.swarthmore.edu/fac-biology/474