Date of Award
© 2017 Alice L. Herneisen. All rights reserved. This work is freely available courtesy of the author. It may only be used for non-commercial, educational, and research purposes. For all other uses, including reproduction and distribution, please contact the copyright holder.
Bachelor of Arts
Chemistry & Biochemistry
Kathleen P. Howard
In my two years working in the Howard lab, I have cycled through a number of projects. These projects fall under the broad context of studying of how the cytoplasmic tail of a particular membrane protein of the influenza A virus, the Matrix protein 2 (M2), is involved in viral budding. I have chosen to present each project in the form of an independent manuscript, with separate Introduction, Experimental, Results, and Discussion sections. Some broader background and theory is briefly provided in Chapters 1 and 2, but Chapters 3-5 are designed to be largely self-contained. Potential future directions pertaining to all three projects are collected in Chapter 6. Science is a collaborative enterprise, and this thesis has benefited from intellectual and experimental contributions from a number of talented collaborators. For the chapters where data is presented (Chapters 3-5), an explanation of the contributions of others is described in a statement at the end of the chapter.
Herneisen, Alice L. , '17, "Conformational Studies of a Domain of the Influenza A M2 Protein Involved in Viral Budding and Morphology" (2017). Senior Theses, Projects, and Awards. 226.