Title

Interaction Of Water-Soluble Porphyrins With Single- And Double-Stranded Polyribonucleotides

Document Type

Article

Publication Date

8-1-1994

Published In

Biopolymers

Abstract

CD and uv-visible absorption studies with several tetracationic water-soluble porphyrin derivatives show that some of these species can serve as probes to discriminate between A- and B-conformational forms of single-stranded polynucleotides. It is also observed that these porphyrins can participate in the formation of double helices by forming transient intermediate complexes enroute to duplex formation. (C) 1994 John Wiley & Sons, Inc.